Incidence of prostatic intra-epithelial neoplasia in Osaka, Japan

Incidence and survival of mesothelioma in Osaka, Japan.

BACKGROUND Mortality statistics show rapid increase in the number of deaths from mesothelioma. However, population-based study of the incidence and the survival has never been conducted. Time-trends and regional differences in the incidence of mesothelioma in Osaka were examined together with their 5-year survival. METHODS Individual data for mesothelioma were retrieved from Osaka Cancer Regi...

Liver X Receptors Protect from Development of Prostatic Intra-Epithelial Neoplasia in Mice

LXR (Liver X Receptors) act as "sensor" proteins that regulate cholesterol uptake, storage, and efflux. LXR signaling is known to influence proliferation of different cell types including human prostatic carcinoma (PCa) cell lines. This study shows that deletion of LXR in mouse fed a high-cholesterol diet recapitulates initial steps of PCa development. Elevation of circulating cholesterol in Lx...

Abstracts, The 13th Annual General Meeting of ARCCNM, Osaka, Japan

Air pollutants in Osaka (Japan)

Increasing emission of anthropogenic particles is causing heavy air pollution. This work intends to analyze the air pollution in Osaka. PM is usually used as an indicator of air quality, because high PM concentrations can degrade air quality. Osaka is the second largest metropolitan region of Japan and its air is significantly polluted by anthropogenic particles emitted from vehicles and indust...

Trends in the incidence of primary intracranial tumors in Osaka, Japan.

We analyzed the trends in the age-standardized incidence rates of 10,460 cases of primary intracranial tumors diagnosed during 1975 and 2004, Osaka, Japan using the Joinpoint regression analysis. During the period 1975-2004, the age-standardized incidence rates of total intracranial tumors increased until 1987 at 3.1% per year and then decreased significantly at -1.8% per year. The time trends ...